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Ravi Vyzasatya Scott E Strome Figure S2, 2A-2HC can cause an initial decrease in platelet count before platelet depletion with MWReg30 that may be the result of platelet sequestration by 2A-2HC.Tumour antigen targeted antibodies (mAbs) can induce natural killer (NK) cells to kill tumours through antibody dependent cellular cytotoxicity (ADCC) upon engagement of NK cell expressed FcγRIIIa.